Medical image segmentation is one of the most important parts of clinical diagnostic tools.The distance regularization effect eliminates the need for reinitialization and thereby avoids its induced numerical errors. DRLSE in which the regularity of the level set function is intrinsically maintained during the level set evolution. The level set evolution is derived as the gradient flow that minimizes energy functional with a distance regularization term and an external energy that drives the motion of the zero level set toward desired locations. The distance regularization term is defined with a potential function such that the derived level set evolution has a unique forward-and-backward (FAB) diffusion effect, which is able to maintain a desired shape of the level set function. Canny operator used to determine the edges and edge directions. Then used a new variation level set formulation that is DRLSE .The algorithm combines the advantages of canny operator which can orient the boundary accurately and the idea that DRLSE algorithm continuously evolves the boundary in image space. Compared different types of Color medical images by using various parameters.