"Fat Chance" takes place in the Florida Keys, a location famous for odd characters and quirky behavior. A steady diet of warm, tropical breezes and frozen drinks brings out the strangest things in people; sometimes even murder. Daphne Schneider has been made fun of most of her life, even by those who supposedly love her. Most people would characterize her unique perspective on life as cold-hearted; Daphne calls it honesty. She never stops to consider whether her short temper, cruel disposition, and excessive drinking are responsible for how people treat her. She blames it on her weight. People are mean to her because she's fat. After relocating to the Keys with her retired Navy pilot husband and young son, Daphne's best friend comes for a short visit. What began as a long weekend to drink and reminisce with Lisa about the good old days turns into a bizarre, permanent arrangement that spurs a landslide. Daphne's husband, John, is a rigid man who dislikes noise or disruption but he uncharacteristically warms to Lisa's loud and carefree ways. Nosy neighbors try to convince Daphne that her husband and best friend are intimate. She pushes away suspicious doubts and tries to rationalize the affectionate relationship developing between them. During a bitter argument with John, he reveals why he married her. Love was never involved. Daphne's world begins to crumble. For the first time in her life, she takes matters into her own hands and fights back. Daphne's crude sense of humor, bolstered by plenty of booze, sees her through several crime sprees. The dead bodies are piling up. Daph never guessed revenge could be so fun. She soon finds out its also addicting.