This volume gathers contributions reflecting topics presented during an INDAM workshop held in Rome in May 2016. The event brought together many prominent researchers in both Mathematical Analysis and Numerical Computing, the goal being to promote interdisciplinary collaborations. Accordingly, the following thematic areas were developed: 1. Lagrangian discretizations and wavefront tracking for synchronization models; 2. Astrophysics computations and post-Newtonian approximations; 3. Hyperbolic balance laws and corrugated isometric embeddings; 4. ¿Caseology¿ techniques for kinetic equations; 5. Tentative computations of compressible non-standard solutions; 6. Entropy dissipation, convergence rates and inverse design issues. Most of the articles are presented in a self-contained manner; some highlight new achievements, while others offer snapshots of the ¿state of the art¿ in certain fields. The book offers a unique resource, both for young researchers looking to quickly enter a given area of application, and for more experienced ones seeking comprehensive overviews and extensive bibliographic references.