Pharmacogenomics: Methods and Protocols -
-35% koodilla BOOKS
Toimitus 17-23 arkipäivässä
30 päivän palautusoikeus
Expert researchers and physician/clinicians describe in detail the newest and most commonly used technologies today in this rapidly advancing field. The authors provide readily reproducible methods for assessing the functional consequences of a certain polymorphism, evaluate the variety of genotyping platforms currently available, and discuss the management of pharmacogenomic information. Highlights include ... Täydellinen kuvaus
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Kuvaus
Expert researchers and physician/clinicians describe in detail the newest and most commonly used technologies today in this rapidly advancing field. The authors provide readily reproducible methods for assessing the functional consequences of a certain polymorphism, evaluate the variety of genotyping platforms currently available, and discuss the management of pharmacogenomic information. Highlights include techniques for making a snapshot of the allele-specific variation in human gene expression, genome wide analysis of allele-specific expression using oligo microarrays, in vivo assays with HaploChIP, SNP genotyping in DNA pools, and PharmGKB, the pharmacogenetics and pharmacogenomics knowledge base. The methodologies for genotyping include denaturing high-performance liquid chromarography, pyrosequencing, kinetic-fluorescence detection, mass spectrometry, and TaqMan assay for insertion/deletions.
Lisätietoja
| Julkaisija | Humana Press |
|---|---|
| Series | Methods in Molecular Biology |
| Julkaisuvuosi | 2005 |
| Kannen tyyppi | Kovakantinen |
| EAN | 9781588294401 |